Endocrine Abstracts

Introduction: Myxedema coma is a medical emergency and can be associated with respiratory failure. Intubated patients have been known to require persistent efforts in ventilator weaning, with one case reported to take 7 months before success.Case report: A 77-year-old gentleman with known primary hypothyroidism presented with chest infection. He had defaulted thyroxine for the past 6 months, relying instead on complementary health products. Thyroid funct...

Introduction: Hypogonadism is known to persist after treatment of hyperprolactinemia, necessitating androgen therapy in young male patients. Aromatisation of testosterone to estradiol can result in tumor expansion. We report a patient with persistent hypogonadism post treatment of macroprolactinoma and discuss challenges involved in the management.Case report: A 51-year-old gentleman was admitted for streptococcal meningitis. Brain imaging revealed a pit...

Introduction: One of the main challenges in the management of male hypogonadotropic hypogonadism (HH) is in the restoration of fertility. We describe 2 patients with HH and discuss the difficulties involved in their management.Case (1): A 23-year-old Chinese man presented with lack of secondary sexual characteristics. Examination revealed Tanner Stage 2 with descended testes measuring 6 ml bilaterally. Laboratory results: total testosterone (TT) <1 n...